Between 2000 and 2009, Jose Lima had the worst ERA among all qualifying starters (6.99 ERA, 5-16) with the 2005 Kansas City Royals.

He also has the second worst ERA in the same period with a 6.65, 7-16 record in 2000 with the Houston Astros. The next worst performance was by Eric Milton in 2005 (6.47 ERA, 8-15 record) with the Cincinnati Reds.