On June 19th, 2001, a San Diego Padres versus San Fransisco Giants game had 40 total strikeouts, 20 thrown from each team.

It is the only time both teams in a game have thrown 20+ strikeouts in a game. 13 of the 14 pitchers in the game contributed to the strikeout total. The game ended in the bottom of the 15th after a single by Phil Nevin, stolen base to second, a wild pitch that left Nevin get to 3rd, and a throwing error letting him score.